Si Cabello ay ipinanganak sa Cojimar , Habana del Este , [[Cuba]] , <ref name="All Music Bio">{{cite web|title=Biography & History|publisher=AllMusic|first=Neil Z.|last=Yeung|url=https://www.allmusic.com/artist/camila-cabello-mn0003392996/biography|accessdate=March 4, 2019}}</ref> kay Sinuhe Estrabao at Alejandro Cabello. Ang kanyang ama ay ipinanganak sa [[Lungsod ng Mehiko|Mexico City]] na lumipat sa Cuba . Mayroon siyang mas bata na kapatid na babae na nagngangalang Sofia. <ref>{{cite news|url=https://www.capitalfm.com/artists/camila-cabello/empowering-message-instagram/|title=Camila Cabello's Empowering Message About Her Sister Is So Important|last=Marti|first=Diana|work=Capital FM|accessdate=March 4, 2019|language=Inglesen-UK}}</ref> Para sa karamihan sa kanyang unang buhay, lumipat si Cabello at ang kanyang pamilya sa pagitan ng Havana at Mexico City, bago lumipat sa [[Miami, Florida]] , sa Estados Unidos nang si Cabello sa edad na lima. <ref name="popsugar">{{cite web|url=http://www.popsugar.com/latina/Camila-Cabello-Her-Cuban-Background-42239921|title=Camila Cabello: 'Our Dreams Were Bigger Than Our Fears'|publisher=PopSugar.com|date=October 5, 2016|first=Camila|last=Cabello|archivedate=November 30, 2016|archiveurl=https://web.archive.org/web/20161130123537/http://www.popsugar.com/latina/Camila-Cabello-Her-Cuban-Background-42239921|url-status=live|quote=...my mom and I immigrated to America. I was almost 7 at the time, born in Havana, Cuba. My papá is puro Mexicano...|df=}}</ref> Si Cabello ay nakuha ang American citizenship noong 2008. <ref>{{cite news|url=http://time.com/collection/american-voices-2017/4927699/american-voices-camila-cabello/|title=Cabello Going Solo|last=Bacle|first=Ariana|date=2017|work=[[Time (magazine)|Time]]|accessdate=March 4, 2019}}</ref> Siya ay pumasok sa Miami Palmetto High School ngunit umalis siya sa pag-aaaral 2012-2013 habang siya ay nasa ika-9 na grado, upang ipagtuloy ang kanyang karera. Pagkaraan ay nakuha niya ang kanyang mataas na paaralan na diploma. <ref>{{cite news|url=https://www.thepalmettopanther.com/qa-with-palmetto-student-camila-cabello/|title=Q&A with Palmetto student Camila Cabello|last=Arguelles|first=Victoria|work=The Panther|accessdate=March 4, 2019|language=Inglesen-US}}</ref>
