Pagkakaiba sa pagitan ng mga pagbago ng "COVID-19"

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Isinaayos ang mga sanggunian
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Tatak: 2017 source edit
m (Isinaayos ang mga sanggunian)
Tatak: 2017 source edit
Pinakanakahahawa ang birus kapag sintomatiko ang mga tao; habang posible ang pagkalat nito bago lumitaw ang mga sintomas, mababa ang panganib.<ref name="CDCTrans" /><!-- Quote = People are thought to be most contagious when they are most symptomatic (the sickest){{nbsp}}... Some spread might be possible before people show symptoms --><ref name="WHO2020QA" /><!-- Quote = The risk of catching COVID-19 from someone with no symptoms at all is very low. --> Sinasabi ng [[European Centre for Disease Prevention and Control|Europeong Sentro sa Pag-iwas at Pagkontrol sa Sakit]] (ECDC) na habang hindi klarong-klaro kung gaano kadali kumalat ang sakit, ang isang tao ay karaniwang nakahahawa sa dalawa o tatlong tao.<ref name="ECDCQA">{{cite web |url=https://www.ecdc.europa.eu/en/novel-coronavirus-china/questions-answers |title=Q & A on COVID-19 |website=European Centre for Disease Prevention and Control |language=en|access-date=23 March 2020}}</ref>
 
Nananatiling "buhay" ang mga birus sa loob ng maraming oras hanggang araw sa mga ibabaw.<ref name="ECDCQA" /><ref name="CDC2020Surfaces" WHO2020QA/><!-- Quote = Current evidence suggests that novel coronavirus may remain viable for hours to days on surfaces made from a variety of materials --><ref name="ECDCQA" /> Para maging tiyak, natuklasan na natutunton ang birus nang hanggang tatlong araw sa plastik at aserong di-kinakalawang, nang isang araw sa karton, at hanggang apat na oras sa tanso.<ref name="Stable NIHStableNIH">{{cite web|url=https://www.nih.gov/news-events/news-releases/new-coronavirus-stable-hours-surfaces|title=New coronavirus stable for hours on surfaces|date=17 March 2020|publisher=[[National Institutes of Health]]|url-status=live|archive-url=https://web.archive.org/web/20200323032520/https://www.nih.gov/news-events/news-releases/new-coronavirus-stable-hours-surfaces|archive-date=23 March 2020|accessdate=23 March 2020}}</ref> Gayunpaman, nagkakaiba-iba ito depende sa kahalumigmigan at temperatura.<ref>{{cite journal |last1=Moriyama |first1=M |last2=Hugentobler |first2=WJ |last3=Iwasaki |first3=A |title=Seasonality of Respiratory Viral Infections. |journal=Annual Review of Virology |date=20 March 2020 |volume=7 |doi=10.1146/annurev-virology-012420-022445 |pmid=32196426}}</ref> Maaaring linisin ang mga ibabaw sa pamamagitan ng mga iilang solusyon (sa loob ng pagkahantad nang isang minuto sa des-impektante para sa ibabaw ng aserong di-kinakalawang). Kabilang dito ang 62–71% [[ethanol]], 50–100% [[isopropanol]], 0.1% [[sodium hypochlorite]], 0.5% [[hydrogen peroxide|agua oksihenada]], at 0.2–7.5% [[povidone-iodine]]. Di-gaanong epetiko ang mga ibang solusyon, tulad ng [[benzalkonium chloride]] at [[chlorhexidine|chrohexidine gluconate]].<ref name="GunterTPS_9days_persistenceSurfacePersistence">{{cite journal |last1=Kampf |first1=G. |last2=Todt |first2=D. |last3=Pfaender |first3=S. |last4=Steinmann |first4=E. |title=Persistence of coronaviruses on inanimate surfaces and their inactivation with biocidal agents |url=https://www.journalofhospitalinfection.com/article/S0195-6701(20)30046-3/fulltext |journal=The Journal of Hospital Infection |volume=104 |issue=3 |pages=246–251 |date=March 2020 |pmid=32035997 |doi=10.1016/j.jhin.2020.01.022}} {{free access}}</ref>
 
=== Birolohiya ===
[[File:Coronavirus virion structure.svg|thumb|Larawan ng ''SARSr-CoV virion'']]
 
Ang SARS-CoV-2 ay isang ''[[novel virus|novel]] severe acute respiratory syndrome coronavirus'', unang ibinukod mula sa tatlong tao na may pulmonya na konektado sa [[Disease cluster|kumpol]] ng kaso ng ''acutematalas respiratoryna sakit sa illness''palahingahan sa Wuhan.<ref name="ECDC risk assessment">{{cite web |url=https://www.ecdc.europa.eu/sites/default/files/documents/SARS-CoV-2-risk-assessment-14-feb-2020.pdf |title=Outbreak of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2): increased transmission beyond China—fourth update |publisher=European Centre for Disease Prevention and Control |date=14 February 2020 |access-date=8 March 2020}}</ref> Makikita ang lahat ng mga katangian ng novel SARS-CoV-2 virus sa mga kaugnay na koronabirus sa kalikasan.<ref name="hcAdONM-20200317">{{cite journal |vauthors=Andersen KG, Rambaut A, Lipkin WI, Holmes EC, Garry RF |title=The proximal origin of SARS-CoV-2 |url=https://www.nature.com/articles/s41591-020-0820-9 |date=17 March 2020 |journal=[[Nature Medicine]] |pages=1–3 |doi=10.1038/s41591-020-0820-9 |issn=1546-170X |access-date=18 March 2020 |archive-url=https://web.archive.org/web/20200318001738/https://www.nature.com/articles/s41591-020-0820-9 |archive-date=18 March 2020 |url-status=live }}</ref>
 
Sa labas ng katawan ng tao, namamatay ang birus sa pamamagitan ng [[soap|sabon]], na nagpapaputok sa bulang pamprotekta ng birus.<ref name=":0">{{Cite journal|last=Salehi|first=Sana|last2=Abedi|first2=Aidin|last3=Balakrishnan|first3=Sudheer|last4=Gholamrezanezhad|first4=Ali|date=2020-03-14|title=Coronavirus Disease 2019 (COVID-19): A Systematic Review of Imaging Findings in 919 Patients|journal=American Journal of Roentgenology|language=en|pages=1–7|doi=10.2214/AJR.20.23034|issn=0361-803X|pmid=32174129}}</ref>
 
Tila may kaugnayan ang SARS-CoV-2 sa orihinal na SARS-CoV.<ref name="Zhu24Jan2020">{{cite journal |vauthors=Zhu N, Zhang D, Wang W, Li X, Yang B, Song J, Zhao X, Huang B, Shi W, Lu R, Niu P, Zhan F, Ma X, Wang D, Xu W, Wu G, Gao GF, Tan W |display-authors=6 |title=A Novel Coronavirus from Patients with Pneumonia in China, 2019 |journal=[[The New England Journal of Medicine]] |volume=382 |issue=8 |pages=727–733 |date=February 2020 |pmid=31978945 |doi=10.1056/NEJMoa2001017}}</ref> Ipinapalagay na nanggaling ito sa [[Zoonosis|hayop]]. Isinisiwalat ng pag-aanalisang henetiko na karaniwang nagtitipun-tipon ang koronabirus sa genus ''[[Betacoronavirus]]'', sa subgenus [[Severe acute respiratory syndrome-related coronavirus|''Sarbecovirus'']] (angkan B) kasama ng dalawang uri na galing-paniki. 96% magkahawig ito at buong antas ng [[genome]] sa mga ibang sampol ng koronabirus sa paniki (BatCov RaTG13).<ref name="WHO report 28 February 2020" /><ref name="bioRxivBatOriginWHOReport24Feb2020" /> Noong Pebrero 2020, natuklasan ng mga Tsinong mananaliksik na isa lamang ang nag-iibang [[asidong amino]] sa mga tiyak na bahagi ng pagkakasunud-sunod ng genome ng mga birus mula sa [[pangolins|pangolin]] at mula sa tao, ngunit natuklasan ng paghahambing ng buong genome sa kasalukuyan na 92% ang pinakamalaking porsyento ng ibinabahaging henetikong materyal sa pagitan ng koronabirus sa pangolin at SARS-CoV-2, na kulang upang patunayan na ang mga pangolin ay [[intermediate host|kalagitnaang biktima]].<ref name="ia56UCyranoski26Feb2020">{{cite journal |title=Mystery deepens over animal source of coronavirus |journal=Nature |volume=579 |pages=18–19 |date=26 February 2020 |doi=10.1038/d41586-020-00548-w |pmid=32127703 |vauthors=Cyranoski D |issue=7797 |bibcode=2020Natur.579...18C}}</ref>
 
== Patopisyolohiya ==
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