Ang doktrina ng pratītyasamutpāda (Sanskrit; Pali: paticcasamuppāda; Tibetan: rten.cing.'brel.bar.'byung.ba; Tsino: 緣起) ay isang mahalagang bahagi ng metapisikang Budista. Ito ay nagsasaad na ang phenomena ay sama-samang lumilitaw sa isang parehong magkakaugnay na sapot ng sanhi at epekto. Ito ay iba ibang isinalin sa Ingles bilang "nakasalalay na pagmumula", "konondisyong henesis"," "nakasalalay na kapwa-paglitaw"," "magkakaugnay na paglitaw," o "kontinhensiya"." Ang pinakamahusay na kilalang aplikasyon ng konsepto ng pratītyasamutpāda ang skema ng [[Labindalawang Nidānas]] (mula sa Pāli na "nidāna" na nangangahulugang "sanhi, pundasyon, pinagmulan") na nagpapaliwanag ng pagpapatuloy ng siklo ng pagdurusa at muling kapanganakan (saṃsāra) sa detalye.<ref>This twelve nidana scheme can be found, for instance, in multiple discourses in chapter 12 of the ''[[Samyutta Nikaya]]''—''Nidana Vagga'' (e.g., see SN 12.2, [http://www.accesstoinsight.org/tipitaka/sn/sn12/sn12.002.than.html Thanissaro, 1997a)]. Other "applications" of what might be termed "mundane dependent origination" include the nine-nidana scheme of ''[[Digha Nikaya]]'' 15 (e.g., [http://www.accesstoinsight.org/tipitaka/dn/dn.15.0.than.html Thanissaro, 1997b)] and the ten-nidana scheme of ''Samyutta Nikaya'' 12.65 (e.g., [http://www.accesstoinsight.org/tipitaka/sn/sn12/sn12.065.than.html Thanissaro, 1997c).] So-called "transcendental dependent origination" (also involving twelve nidanas) is described in ''Samyutta Nikaya'' 12.23 (e.g., see [http://www.accesstoinsight.org/lib/authors/bodhi/wheel277.html Bodhi, 1995).] In addition, Digha Nikaya 15 describes an eleven-nidana scheme (starting with "feeling") that leads to interpersonal suffering ("the taking up of sticks and knives; conflicts, quarrels, and disputes; accusations, divisive speech, and lies").</ref>
