Kanser: Pagkakaiba sa mga binago

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Glennznl (usapan | ambag)
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Linya 142:
Ang konsepto ng mga medikasyon o gamot ay maaaring gamitin upang maiwasan ang kansr ay nakaaakit at ang ebidensiya ay sumusuporta sa paggamit ng mga ito sa ilang mga inilarawang sirkunstansiya.<ref>Holland Chp.33</ref> Sa pangkalahatang populasyon, ang mga [[NSAID]] ay nagpapabwas ng panganib ng [[kanser na colorectal]] gayunpaman, sanhi ng mga side effect na cardiovascular at gastrointestinal, ang mga ito ay nagsasanhi ng pangkabuuang panganib kapag ginamit sa pag-iwas ng kanser.<ref name="pmid17339623">{{cite journal | author = Rostom A, Dubé C, Lewin G, Tsertsvadze A, Barrowman N, Code C, Sampson M, Moher D | title = Nonsteroidal anti-inflammatory drugs and cyclooxygenase-2 inhibitors for primary prevention of colorectal cancer: a systematic review prepared for the U.S. Preventive Services Task Force | journal = Ann. Intern. Med. | volume = 146 | issue = 5 | pages = 376–89 | year = 2007 | month = March | pmid = 17339623 | doi = }}</ref> [[Aspirin]] has been found to reduce the risk of death from cancer by about 7%.<ref name="pmid21144578">{{cite journal | author = Rothwell PM, Fowkes FG, Belch JF, Ogawa H, Warlow CP, Meade TW | title = Effect of daily aspirin on long-term risk of death due to cancer: analysis of individual patient data from randomised trials | journal = Lancet | volume = 377 | issue = 9759 | pages = 31–41 | year = 2011 | month = January | pmid = 21144578 | doi = 10.1016/S0140-6736(10)62110-1 }}</ref> Ang [[tagapigil ng COX-2]] ay maaaring magpabawa ng rate ng pagkakabuo ng [[polyp]] sa mga taong may [[familial adenomatous polyposis]] gayunpaman, ay nauugnay ang mga ito sa parehong mga adbersong epekto gaya ng mga NSAID.<ref name="pmid20594533">{{cite journal | author = Cooper K, Squires H, Carroll C, Papaioannou D, Booth A, Logan RF, Maguire C, Hind D, Tappenden P | title = Chemoprevention of colorectal cancer: systematic review and economic evaluation | journal = Health Technol Assess | volume = 14 | issue = 32 | pages = 1–206 | year = 2010 | month = June | pmid = 20594533 | doi = 10.3310/hta14320 }}</ref> Ang pang-araw araw na paggamit ng[[tamoxifen]] o [[raloxifene]] ay naipakitang nagpapabawas ng pagkakaron ng [[kanser sa suso]] sa mataas na panganib na mga babae.<ref name="pmid19020189">{{cite journal | author = Thomsen A, Kolesar JM | title = Chemoprevention of breast cancer | journal = Am J Health Syst Pharm | volume = 65 | issue = 23 | pages = 2221–8 | year = 2008 | month = December | pmid = 19020189 | doi = 10.2146/ajhp070663 }}</ref> Ang benepisyo laban sa panganib para sa [[tagapigil ng 5-alpha-reductase]] gaya ng [[finasteride]] ay hindi maliwanag.<ref name="pmid18425978">{{cite journal | author = Wilt TJ, MacDonald R, Hagerty K, Schellhammer P, Kramer BS | title = Five-alpha-reductase Inhibitors for prostate cancer prevention | journal = Cochrane Database Syst Rev | volume = | issue = 2 | pages = CD007091 | year = 2008 | pmid = 18425978 | doi = 10.1002/14651858.CD007091 }}</ref>
 
Ang mga [[bitamina]] ay hidni natagpuang epektibo sa pag-iwas ng kanser,<ref name="pmid20939459">{{cite journal | author = | title = Vitamins and minerals: not for cancer or cardiovascular prevention | journal = Prescrire Int | volume = 19 | issue = 108 | pages = 182 | year = 2010 | month = August | pmid = 20939459 | doi = | url = http://english.prescrire.org/en/81/168/46461/0/2010/ArchiveNewsDetails.aspx?page=2 }}</ref> bagaman ang mababang mga lebel ng [[bitamina D]] ay nauugnay sa tumaas na panganib ng kanser.<ref name="pmid16595781">{{cite journal | author = Giovannucci E, Liu Y, Rimm EB, Hollis BW, Fuchs CS, Stampfer MJ, Willett WC | title = Prospective study of predictors of vitamin D status and cancer incidence and mortality in men | journal = J. Natl. Cancer Inst. | volume = 98 | issue = 7 | pages = 451–9 | year = 2006 | month = April | pmid = 16595781 | doi = 10.1093/jnci/djj101 }}</ref><ref>{{cite web|url=http://www.cancer.org/docroot/NWS/content/NWS_1_1x_Vitamin_D_Has_Role_in_Colon_Cancer_Prevention.asp|title=Vitamin D Has Role in Colon Cancer Prevention|accessdate=27 Hulyo 2007 | archiveurl = httphttps://web.archive.org/web/20061204052746/http://www.cancer.org/docroot/NWS/content/NWS_1_1x_Vitamin_D_Has_Role_in_Colon_Cancer_Prevention.asp| archivedate = 4 Disyembre 2006 -12-04|url-status=live}}</ref> Whether this relationship is causal and vitamin D supplementation is protective is not determined.<ref name="pmid16595770">{{cite journal | author = Schwartz GG, Blot WJ | title = Vitamin D status and cancer incidence and mortality: something new under the sun | journal = J. Natl. Cancer Inst. | volume = 98 | issue = 7 | pages = 428–30 | year = 2006 | month = April | pmid = 16595770 | doi = 10.1093/jnci/djj127 }}</ref> Ang pag-inom ng mga suplement na [[Beta-carotene]] ay natagpuang nagpapataas ng mga rate ng [[kanser sa baga]] sa mga mataas na panganib na tao.<ref name="pmid21738614">{{cite journal | author = Fritz H, Kennedy D, Fergusson D, Fernandes R, Doucette S, Cooley K, Seely A, Sagar S, Wong R, Seely D | title = Vitamin A and retinoid derivatives for lung cancer: a systematic review and meta analysis | journal = PLoS ONE | volume = 6 | issue = 6 | pages = e21107 | year = 2011 | pmid = 21738614 | pmc = 3124481 | doi = 10.1371/journal.pone.0021107 }}</ref> Ang suplementasyon ng [[asidong folic]] ay hindi natagpuang epektibo sa pag-iwas ng [[kanser sa colon]] at maaaring magpataas ng mga polyp sa colon.<ref name="pmid17551129">{{cite journal | author = Cole BF, Baron JA, Sandler RS, Haile RW, Ahnen DJ, Bresalier RS, McKeown-Eyssen G, Summers RW, Rothstein RI, Burke CA, Snover DC, Church TR, Allen JI, Robertson DJ, Beck GJ, Bond JH, Byers T, Mandel JS, Mott LA, Pearson LH, Barry EL, Rees JR, Marcon N, Saibil F, Ueland PM, Greenberg ER | title = Folic acid for the prevention of colorectal adenomas: a randomized clinical trial | journal = JAMA | volume = 297 | issue = 21 | pages = 2351–9 | year = 2007 | month = June | pmid = 17551129 | doi = 10.1001/jama.297.21.2351 }}</ref>
 
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